Assay Detail
Binding
CHEMBL645379
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Binding affinity was tested on CEC-pretreated rat hippocampus Alpha-1A adrenergic receptor
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Hippocampus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Pharmacological options in the treatment of benign prostatic hyperplasia.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 8.56 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL25098 | — | — | 1 | 9.00 |
| CHEMBL278518 | — | — | 1 | 9.00 |
| CHEMBL27341 | — | — | 1 | 8.82 |
| CHEMBL278865 | UPIDOSIN | 2.0 | 1 | 8.70 |
| CHEMBL24629 | — | — | 1 | 8.00 |
| CHEMBL25012 | — | — | 1 | 7.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL25098 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL278518 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL27341 | — | IC50 | = | 1.5 | nM | 8.82 |
| CHEMBL278865 | UPIDOSIN | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL24629 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL25012 | — | IC50 | = | 14.0 | nM | 7.85 |