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Assay Detail

CHEMBL645399

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Binding
Inhibition constant against mammalian liver alcohol dehydrogenase (ADH)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Equus caballus
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Alcohol dehydrogenase 1A (CHEMBL1970)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

CNAD: a potent and specific inhibitor of alcohol dehydrogenase.
Goldstein BM, Li H, Jones JP, Bell JE, Zeidler J, Pankiewicz KW, Watanabe KA.
J Med Chem (1994) 37 : 392 -399
PubMed 8308865 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 7.40 8.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1231859 1 8.40
CHEMBL1161866 1 6.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1231859 Ki = 4.0 nM 8.40
CHEMBL1161866 Ki = 400.0 nM 6.40