Assay Detail
Binding
CHEMBL645580
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Inhibition of arginylaminopeptidase (aminopeptidase B)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Oryctolagus cuniculus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Investigation of the active site of aminopeptidase A using a series of new thiol-containing inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.10 | 9.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL432852 | — | — | 1 | 9.05 |
| CHEMBL27163 | — | — | 1 | 7.96 |
| CHEMBL27010 | — | — | 1 | 7.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL432852 | — | Ki | = | 0.9 | nM | 9.05 |
| CHEMBL27163 | — | Ki | = | 11.0 | nM | 7.96 |
| CHEMBL27010 | — | Ki | = | 51.0 | nM | 7.29 |