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Assay Detail

CHEMBL645605

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was evaluated for inhibition of binding of [3H]MK-91 to Alpha-2 adrenergic receptor in hamster adipocytes
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Cricetulus griseus
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Adrenergic receptor alpha-2 (CHEMBL2095158)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Alpha- and beta-adrenoceptors: from the gene to the clinic. 1. Molecular biology and adrenoceptor subclassification.
Hieble JP, Bondinell WE, Ruffolo RR.
J Med Chem (1995) 38 : 3415 -3444
PubMed 7658428 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.52 8.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL762 OXYMETAZOLINE 4.0 1 8.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL762 OXYMETAZOLINE Ki = 3.0 nM 8.52