Assay Detail
Binding
CHEMBL645618
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Binding affinity towards Alpha-2 adrenergic receptor of HT-29 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | HT-29 |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Analogs of UK 14,304 as 2-adrenoceptor agonists. Twist and agent polarity as design elements.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 8.62 | 8.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL844 | BRIMONIDINE | 4.0 | 1 | 8.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL844 | BRIMONIDINE | Ki | = | 2.4 | nM | 8.62 |