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Assay Detail

CHEMBL645857

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was evaluated for the inhibition of infectivity and cytopathic effect of HIV-1 in ATH8 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type ATH-8
Confidence 1 — Organism
Curated By Intermediate

Target

ATH-8 cell line (CHEMBL614273)
Type CELL-LINE
Organism Homo sapiens

Publication

Phosphodiester amidates of allenic nucleoside analogues: anti-HIV activity and possible mechanism of action.
Winter H, Maeda Y, Mitsuya H, Zemlicka J.
J Med Chem (1996) 39 : 3300 -3306
PubMed 8765513 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.52 5.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL313478 1 5.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL313478 IC50 = 3000.0 nM 5.52