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Assay Detail

CHEMBL645858

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibitory activity against HIV-1 in ATH8 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type ATH-8
Confidence 1 — Organism
Curated By Intermediate

Target

ATH-8 cell line (CHEMBL614273)
Type CELL-LINE
Organism Homo sapiens

Publication

Unsaturated acyclic analogues of 2'-deoxyadenosine and thymidine containing fluorine: synthesis and biological activity.
Xu ZQ, Qiu YL, Chokekijchai S, Mitsuya H, Zemlicka J.
J Med Chem (1995) 38 : 875 -882
PubMed 7699702 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.00 4.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL352577 1 4.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL352577 IC50 = 100000.0 nM 4.00