Assay Detail
Binding
CHEMBL645902
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Binding affinity towards Alpha-2 adrenergic receptor
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Benzylimidazolines as h5-HT1B/1D serotonin receptor ligands: a structure-affinity investigation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 5.92 | 5.95 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL308727 | — | — | 1 | 5.95 |
| CHEMBL72107 | — | — | 1 | 5.88 |
| CHEMBL762 | OXYMETAZOLINE | 4.0 | 1 | - |
| CHEMBL70409 | — | — | 1 | - |
| CHEMBL312448 | XYLOMETAZOLINE | 3.0 | 1 | - |
| CHEMBL308042 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL308727 | — | Ki | = | 1120.0 | nM | 5.95 |
| CHEMBL72107 | — | Ki | = | 1320.0 | nM | 5.88 |
| CHEMBL762 | OXYMETAZOLINE | Ki | > | 500.0 | nM | - |
| CHEMBL70409 | — | Ki | > | 500.0 | nM | - |
| CHEMBL312448 | XYLOMETAZOLINE | Ki | > | 500.0 | nM | - |
| CHEMBL308042 | — | Ki | > | 500.0 | nM | - |