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Assay Detail

CHEMBL646245

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Overall binding displacement in tissues containing only the Alpha-1B adrenergic receptor (rat spleen, rat liver)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Tissue Spleen
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Alpha-1D adrenergic receptor (CHEMBL326)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Alpha- and beta-adrenoceptors: from the gene to the clinic. 1. Molecular biology and adrenoceptor subclassification.
Hieble JP, Bondinell WE, Ruffolo RR.
J Med Chem (1995) 38 : 3415 -3444
PubMed 7658428 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.02 7.02

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL420060 1 7.02

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL420060 Ki = 96.0 nM 7.02