Assay Detail
Binding
CHEMBL646260
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Compound was tested for the adenylate cyclase stimulation
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
A study on the contribution of the 1-phenyl substituent to the molecular electrostatic potentials of some benzazepines in relation to selective dopamine D-1 receptor activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.22 | 7.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL24077 | (R)-SKF-38393 | — | 1 | 7.15 |
| CHEMBL57873 | — | — | 1 | 5.28 |
| CHEMBL146629 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL24077 | (R)-SKF-38393 | EC50 | = | 71.0 | nM | 7.15 |
| CHEMBL57873 | — | EC50 | = | 5200.0 | nM | 5.28 |
| CHEMBL146629 | — | EC50 | > | 10000.0 | nM | - |