Assay Detail
Binding
CHEMBL646266
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Effective concentration required to stimulate Adenylate cyclase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Conformational analysis and structure-activity relationships of selective dopamine D-1 receptor agonists and antagonists of the benzazepine series.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.89 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL24077 | (R)-SKF-38393 | — | 1 | 7.10 |
| CHEMBL68922 | — | — | 1 | 6.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL24077 | (R)-SKF-38393 | EC50 | = | 80.0 | nM | 7.10 |
| CHEMBL68922 | — | EC50 | = | 210.0 | nM | 6.68 |