Assay Detail
Binding
CHEMBL646603
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [125I]AB-MECA from human Adenosine A3 receptor expressed in HEK293 cell membrane
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Tetrahydrobenzothiophenone derivatives as a novel class of adenosine receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 4.45 | 4.45 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL337243 | — | — | 1 | 4.45 |
| CHEMBL336968 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL337243 | — | Ki | = | 35800.0 | nM | 4.45 |
| CHEMBL336968 | — | Ki | = | 117000.0 | nM | - |