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Assay Detail

CHEMBL646820

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was evaluated for the ability to inhibit binding of [3H]nitrendipine to membrane homogenates of of rat alpha-2D adrenergic receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Alpha-2A adrenergic receptor (CHEMBL327)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Alpha- and beta-adrenoceptors: from the gene to the clinic. 2. Structure-activity relationships and therapeutic applications.
Ruffolo RR, Bondinell W, Hieble JP.
J Med Chem (1995) 38 : 3681 -3716
PubMed 7562902 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.92 5.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL122404 AKUAMMIGINE 1 5.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL122404 AKUAMMIGINE Ki = 1210.0 nM 5.92