Assay Detail
Binding
CHEMBL646883
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Inhibitory activity towards Alpha-glucosidase from Baker yeast (isomaltase)
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces cerevisiae |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Derivatives of (2R,3R,4S)-2-aminomethylpyrrolidine-3,4-diol are selective alpha-mannosidase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 4.25 | 4.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL82895 | — | — | 1 | 4.40 |
| CHEMBL84272 | — | — | 1 | 4.40 |
| CHEMBL313295 | — | — | 1 | 4.35 |
| CHEMBL84940 | — | — | 1 | 4.15 |
| CHEMBL2206827 | — | — | 1 | 4.11 |
| CHEMBL2206826 | — | — | 1 | 4.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL82895 | — | Ki | = | 40000.0 | nM | 4.40 |
| CHEMBL84272 | — | Ki | = | 40000.0 | nM | 4.40 |
| CHEMBL313295 | — | Ki | = | 45000.0 | nM | 4.35 |
| CHEMBL84940 | — | Ki | = | 71000.0 | nM | 4.15 |
| CHEMBL2206827 | — | Ki | = | 77000.0 | nM | 4.11 |
| CHEMBL2206826 | — | Ki | = | 83000.0 | nM | 4.08 |