Assay Detail
Functional
CHEMBL646977
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for in vitro for AII receptor antagonistic activity in bovine adrenal cortex.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Tissue | Adrenal cortex |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of the potent isoxazolidinyl angiotensin II receptor antagonist CL332,877 and its enantiomers.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.02 | 8.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL408033 | — | — | 1 | 8.46 |
| CHEMBL7550 | L-158809 | — | 1 | 7.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL408033 | — | IC50 | = | 3.5 | nM | 8.46 |
| CHEMBL7550 | L-158809 | IC50 | = | 27.0 | nM | 7.57 |