Assay Detail
Binding
CHEMBL647115
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50% Inhibitory potency against angiotensin I converting enzyme from mouse striatum.
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
New carboxyalkyl inhibitors of brain enkephalinase: synthesis, biological activity, and analgesic properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.27 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2372593 | — | — | 1 | 5.70 |
| CHEMBL2372595 | — | — | 1 | 5.40 |
| CHEMBL1161396 | — | — | 1 | 4.70 |
| CHEMBL1161399 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2372593 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL2372595 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL1161396 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL1161399 | — | IC50 | > | 100000.0 | nM | - |