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Assay Detail

CHEMBL647121

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition constant against Angiotensin II receptor, type 1 was determined
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Type-1 angiotensin II receptor (CHEMBL227)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Angiotensin II AT1 receptor antagonists. Clinical implications of active metabolites.
Schmidt B, Schieffer B.
J Med Chem (2003) 46 : 2261 -2270
PubMed 12773029 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 5.88 6.43

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL74767 1 6.43
CHEMBL1069 VALSARTAN 4.0 1 5.33

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL74767 Ki = 370.0 nM 6.43
CHEMBL1069 VALSARTAN Ki = 4700.0 nM 5.33