Assay Detail
Binding
CHEMBL647513
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In vitro binding affinity of compound was measured against angiotensin II (AT2) receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
L-161,638: A potent AT2selective quinazolinone angiotensin II binding inhibitor
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.31 | 9.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL34124 | OLODANRIGAN | 2.0 | 1 | 9.24 |
| CHEMBL157946 | — | — | 1 | 8.16 |
| CHEMBL290286 | — | — | 1 | 7.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL34124 | OLODANRIGAN | IC50 | = | 0.58 | nM | 9.24 |
| CHEMBL157946 | — | IC50 | = | 6.9 | nM | 8.16 |
| CHEMBL290286 | — | IC50 | = | 30.0 | nM | 7.52 |