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Assay Detail

CHEMBL647606

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory activity against baker's yeast Alpha-galactosidase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Saccharomyces cerevisiae
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Lysosomal alpha-glucosidase (CHEMBL2608)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Potent glycosidase inhibitors, N-phenyl cyclic isourea derivatives of 5-amino- and 5-amino-1-C-(hydroxymethyl)-cyclopentane-1,2,3,4-tetraols
Uchida C, Kimura H, Ogawa S
Bioorg Med Chem Lett (1994) 4 : 2643 -2648
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.87 5.87

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL88413 1 5.87

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL88413 IC50 = 1340.0 nM 5.87