Assay Detail
Binding
CHEMBL647727
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for binding affinity against Alpha-2A adrenergic receptor from human clones.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Alpha- and beta-adrenoceptors: from the gene to the clinic. 1. Molecular biology and adrenoceptor subclassification.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.82 | 8.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL597 | PHENTOLAMINE | 4.0 | 1 | 8.59 |
| CHEMBL420060 | — | — | 1 | 6.21 |
| CHEMBL279516 | INDORAMIN | 2.0 | 1 | 5.65 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL597 | PHENTOLAMINE | Ki | = | 2.6 | nM | 8.59 |
| CHEMBL420060 | — | Ki | = | 612.0 | nM | 6.21 |
| CHEMBL279516 | INDORAMIN | Ki | = | 2240.0 | nM | 5.65 |