Assay Detail
Binding
CHEMBL647852
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Compound was evaluated for inhibition of Angiotensin II receptor, type 2 in rat midbrain AT2 assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Midbrain |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and structure-activity relationships of a novel series of non-peptide AT2-selective angiotensin II receptor antagonists
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.07 | 7.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL294558 | — | — | 1 | 7.42 |
| CHEMBL292277 | — | — | 1 | 6.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL294558 | — | IC50 | = | 38.0 | nM | 7.42 |
| CHEMBL292277 | — | IC50 | = | 190.0 | nM | 6.72 |