Assay Detail
Binding
CHEMBL647933
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liver
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Liver |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Inhibition of aminopeptidases by peptides containing ketomethylene and hydroxyethylene amide bond replacements.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.51 | 9.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL281437 | — | — | 1 | 9.08 |
| CHEMBL282583 | — | — | 1 | 8.60 |
| CHEMBL29292 | UBENIMEX | 2.0 | 1 | 7.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL281437 | — | Ki | = | 0.84 | nM | 9.08 |
| CHEMBL282583 | — | Ki | = | 2.5 | nM | 8.60 |
| CHEMBL29292 | UBENIMEX | Ki | = | 14.0 | nM | 7.85 |