Assay Detail
Binding
CHEMBL648348
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Concentration required for 50% inhibition of Angiotensin I converting enzyme
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Angiotensin converting enzyme inhibitors: modifications of a tripeptide analogue.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 7.14 | 8.49 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL435360 | — | — | 1 | 8.49 |
| CHEMBL366420 | — | — | 1 | 8.36 |
| CHEMBL177842 | — | — | 1 | 7.92 |
| CHEMBL367334 | — | — | 1 | 7.38 |
| CHEMBL360536 | — | — | 1 | 6.02 |
| CHEMBL366372 | — | — | 1 | 4.66 |
| CHEMBL175468 | — | — | 1 | - |
| CHEMBL440556 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL435360 | — | IC50 | = | 3.2 | nM | 8.49 |
| CHEMBL366420 | — | IC50 | = | 4.4 | nM | 8.36 |
| CHEMBL177842 | — | IC50 | = | 12.0 | nM | 7.92 |
| CHEMBL367334 | — | IC50 | = | 42.0 | nM | 7.38 |
| CHEMBL360536 | — | IC50 | = | 960.0 | nM | 6.02 |
| CHEMBL366372 | — | IC50 | = | 22000.0 | nM | 4.66 |
| CHEMBL175468 | — | IC50 | - | nM | - | |
| CHEMBL440556 | — | IC50 | - | nM | - |