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Assay Detail

CHEMBL648572

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Ki value was evaluated against Angiotensin II receptor, type 1
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Type-1 angiotensin II receptor (CHEMBL227)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy.
Wexler RR, Greenlee WJ, Irvin JD, Goldberg MR, Prendergast K, Smith RD, Timmermans PB.
J Med Chem (1996) 39 : 625 -656
PubMed 8576904 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 7.62 7.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL348126 1 7.70
CHEMBL130896 1 7.54

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL348126 Ki = 20.0 nM 7.70
CHEMBL130896 Ki = 29.0 nM 7.54