Assay Detail
Binding
CHEMBL648630
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was evaluated for its affinity for Alpha-1a adrenergic receptor in dog prostate tissue preparations
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Canis lupus familiaris |
| Tissue | Prostate gland |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Design and synthesis of N-alkylated saccharins as selective alpha-1a adrenergic receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.56 | 9.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL313990 | — | — | 1 | 9.62 |
| CHEMBL611 | TERAZOSIN | 4.0 | 1 | 7.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL313990 | — | Ki | = | 0.24 | nM | 9.62 |
| CHEMBL611 | TERAZOSIN | Ki | = | 32.0 | nM | 7.50 |