Assay Detail
Binding
CHEMBL648793
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for its binding affinity towards Rat-1 cells stably expressing hamster alpha-1b adrenergic receptor by displacing [125I]HEAT (2-beta-(4-hydroxyphenyl)-ethylaminomethyltetralone)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | Rat-1 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Marine sponge bis(indole) alkaloids that displace ligand binding to 1 adrenergic receptors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 5.32 | 5.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL303282 | TOPSENTIN | — | 1 | 5.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL303282 | TOPSENTIN | Ki | = | 4740.0 | nM | 5.32 |