Assay Detail
Binding
CHEMBL649181
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In vivo binding affinity was evaluated against Alpha-1 adrenergic receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Isoindolinone enantiomers having affinity for the dopamine D4 receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.68 | 6.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL35093 | — | — | 1 | 6.90 |
| CHEMBL37170 | — | — | 1 | 6.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL35093 | — | Ki | = | 127.0 | nM | 6.90 |
| CHEMBL37170 | — | Ki | = | 343.0 | nM | 6.46 |