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Assay Detail

CHEMBL649262

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Binding
Inhibitory activity towards Alpha-glucosidase from Rhizopus mold (amyloglucosidase)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rhizopus arrhizus
Confidence 9 — Direct single protein target
Curated By Expert

Target

Glucoamylase 1 (CHEMBL4449)
Type SINGLE PROTEIN
Organism Rhizopus oryzae

Publication

Derivatives of (2R,3R,4S)-2-aminomethylpyrrolidine-3,4-diol are selective alpha-mannosidase inhibitors.
Popowycz F, Gerber-Lemaire S, Demange R, Rodriguez-García E, Asenjo AT, Robina I, Vogel P.
Bioorg Med Chem Lett (2001) 11 : 2489 -2493
PubMed 11549453 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.70 4.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2115197 1 4.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2115197 IC50 = 20000.0 nM 4.70