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Assay Detail

CHEMBL649514

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Tested in vitro for amylase release from rat pancreatic acini (% of amylase secretion at 1 mM)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Pancreatic alpha-amylase (CHEMBL2045)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthesis and biological evaluation of cholecystokinin analogs in which the Asp-Phe-NH2 moiety has been replaced by a 3-amino-7-phenylheptanoic acid or a 3-amino-6-(phenyloxy)hexanoic acid.
Amblard M, Rodriguez M, Lignon MF, Galas MC, Bernad N, Artis-Noël AM, Hauad L, Laur J, Califano JC, Aumelas A.
J Med Chem (1993) 36 : 3021 -3028
PubMed 7692048 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 7.66 7.66

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL444113 1 7.66

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL444113 EC50 = 22.0 nM 7.66