Assay Detail
Binding
CHEMBL649567
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The compound was tested for the inhibitory activity against alpha-L-Fucosidase in bovine kidney
7
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis of an alpha-fucosidase inhibitor, 5a-carba-beta-L-fucopyranosylamine, and fucose-type alpha- and beta-DL-valienamine unsaturated derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.13 | 7.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2115269 | — | — | 2 | 7.92 |
| CHEMBL2114287 | — | — | 1 | 7.92 |
| CHEMBL162540 | — | — | 2 | 5.55 |
| CHEMBL541713 | — | — | 2 | 4.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2115269 | — | Ki | = | 12.0 | nM | 7.92 |
| CHEMBL2114287 | — | Ki | = | 12.0 | nM | 7.92 |
| CHEMBL2115269 | — | Ki | = | 200.0 | nM | 6.70 |
| CHEMBL162540 | — | Ki | = | 2800.0 | nM | 5.55 |
| CHEMBL162540 | — | Ki | = | 3000.0 | nM | 5.52 |
| CHEMBL541713 | — | Ki | = | 12000.0 | nM | 4.92 |
| CHEMBL541713 | — | Ki | = | 45000.0 | nM | 4.35 |