Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL649568

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory activity against alpha-L-fucosidase of bacillus species (K40T) expressed as Ki
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bacillus sp.
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Tissue alpha-L-fucosidase (CHEMBL4176)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

New leads for selective inhibitors of alpha-L-fucosidases. Synthesis and glycosidase inhibitory activities of [(2R,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]furan derivatives.
Robina I, Moreno-Vargas AJ, Fernández-Bolaños JG, Fuentes J, Demange R, Vogel P.
Bioorg Med Chem Lett (2001) 11 : 2555 -2559
PubMed 11549468 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.68 6.68

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL85817 1 6.68

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL85817 Ki = 210.0 nM 6.68