Assay Detail
Binding
CHEMBL649589
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Inhibitory activity against alpha-L-fucosidase of bovine epididymis expressed as Ki
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
New leads for selective inhibitors of alpha-L-fucosidases. Synthesis and glycosidase inhibitory activities of [(2R,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]furan derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.39 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL87463 | — | — | 1 | 8.22 |
| CHEMBL85773 | — | — | 1 | 8.15 |
| CHEMBL84901 | — | — | 1 | 4.63 |
| CHEMBL3349555 | — | — | 1 | 4.55 |
| CHEMBL2207396 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL87463 | — | Ki | = | 6.0 | nM | 8.22 |
| CHEMBL85773 | — | Ki | = | 7.0 | nM | 8.15 |
| CHEMBL84901 | — | Ki | = | 23400.0 | nM | 4.63 |
| CHEMBL3349555 | — | Ki | = | 28000.0 | nM | 4.55 |
| CHEMBL2207396 | — | Ki | > | 1000000.0 | nM | - |