Assay Detail
Binding
CHEMBL649591
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Inhibitory activity measured against alpha-L-fucosidase of bovine epididymis by colorimetric assay using the D-glucose oxidase-peroxidase method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Homonojirimycin isomers and N-alkylated homonojirimycins: structural and conformational basis of inhibition of glycosidases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.51 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL87474 | — | — | 1 | 7.10 |
| CHEMBL314772 | DEOXYFUCONOJIRIMYCIN | — | 1 | 7.10 |
| CHEMBL84844 | DEOXYMANNOJIRIMYCIN | — | 1 | 5.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL87474 | — | Ki | = | 80.0 | nM | 7.10 |
| CHEMBL314772 | DEOXYFUCONOJIRIMYCIN | Ki | = | 80.0 | nM | 7.10 |
| CHEMBL84844 | DEOXYMANNOJIRIMYCIN | Ki | = | 4700.0 | nM | 5.33 |