Assay Detail
Binding
CHEMBL649604
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for binding affinity against Alpha-1 adrenergic receptor using WB-4101 as radioligand
4
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Conformational properties of semirigid antipsychotic drugs: the pharmacophore for dopamine D-2 antagonist activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 7.19 | 7.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL45491 | — | — | 2 | 7.92 |
| CHEMBL300647 | — | — | 2 | 7.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL45491 | — | Ki | = | 12.0 | nM | 7.92 |
| CHEMBL300647 | — | Ki | = | 36.0 | nM | 7.44 |
| CHEMBL300647 | — | Ki | = | 61.0 | nM | 7.21 |
| CHEMBL45491 | — | Ki | = | 680.0 | nM | 6.17 |