Assay Detail
Binding
CHEMBL649764
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pA2 value at human Adenosine A2B receptor from Schild plots with slopes approaching unity
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Derivatives of the triazoloquinazoline adenosine antagonist (CGS 15943) having high potency at the human A2B and A3 receptor subtypes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 8.00 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL95811 | — | — | 1 | 8.00 |
| CHEMBL16687 | CGS-15943 | — | 1 | 8.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL95811 | — | Kd | = | 10.0 | nM | 8.00 |
| CHEMBL16687 | CGS-15943 | Kd | = | 10.0 | nM | 8.00 |