Assay Detail
Binding
CHEMBL649909
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro functional activity at Alpha-1A adrenergic receptor in rat vas deferens
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Vas deferens |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Two novel and potent 3-[(o-methoxyphenyl)piperazinylethyl]-5-phenylthien.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 7.47 | 8.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL13856 | A-123189 | — | 1 | 8.36 |
| CHEMBL268758 | A-119637 | — | 1 | 8.07 |
| CHEMBL13647 | BMY-7378 | — | 1 | 5.98 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL13856 | A-123189 | Kd | = | 4.365 | nM | 8.36 |
| CHEMBL268758 | A-119637 | Kd | = | 8.511 | nM | 8.07 |
| CHEMBL13647 | BMY-7378 | Kd | = | 1047.13 | nM | 5.98 |