Assay Detail
Functional
CHEMBL650069
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inverse agonist activity at GABA-A benzodiazepine receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Target
GABA-A receptor; anion channel (CHEMBL2093872) ↗| Type | PROTEIN COMPLEX GROUP |
| Organism | Homo sapiens |
Publication
Simple linear QSAR models based on quantum similarity measures.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.84 | 7.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL148858 | — | — | 1 | 7.32 |
| CHEMBL278470 | — | — | 1 | 6.74 |
| CHEMBL358763 | — | — | 1 | 6.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL148858 | — | Ki | = | 47.86 | nM | 7.32 |
| CHEMBL278470 | — | Ki | = | 181.97 | nM | 6.74 |
| CHEMBL358763 | — | Ki | = | 346.74 | nM | 6.46 |