Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL650292

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity against angiotensin II receptor type 2 (AT2) of rat adrenal medulla.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Expert

Target

Type-2 angiotensin II receptor (CHEMBL257)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Non-peptide angiotensin II receptor antagonists: synthesis and biological activity of a series of novel 4,5-dihydro-4-oxo-3H-imidazo[4,5-c]pyridine derivatives.
Mederski WW, Dorsch D, Bokel HH, Beier N, Lues I, Schelling P.
J Med Chem (1994) 37 : 1632 -1645
PubMed 8201597 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.52 6.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL42101 1 6.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL42101 Ki = 300.0 nM 6.52