Assay Detail
Binding
CHEMBL650314
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In vivo inhibitory concentration against Angiotensin II receptor, type 1 of rat adrenal membrane
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Development of angiotensin II antagonists with equipotent affinity for human AT1 and AT2 receptor subtypes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.28 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL74476 | — | — | 1 | 8.40 |
| CHEMBL302102 | — | — | 1 | 8.15 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL74476 | — | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL302102 | — | IC50 | = | 7.0 | nM | 8.15 |