Assay Detail
Functional
CHEMBL650531
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective dose to achieve 50% protection of C8166 cells acutely infected with HIV-2 strain IIIB
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | C8166 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Decomposition pathways and in vitro HIV inhibitory effects of isoddA pronucleotides: toward a rational approach for intracellular delivery of nucleoside 5'-monophosphates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 7.70 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL291344 | — | — | 1 | 7.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL291344 | — | EC50 | = | 20.0 | nM | 7.70 |