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Assay Detail

CHEMBL651096

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory concentration against AT2 receptor from rat adrenal tissues.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Type-2 angiotensin II receptor (CHEMBL257)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Potent triazolinone-based angiotensin II receptor antagonists with equivalent affinity for both the AT1 and AT2 subtypes
Chang L, Ashton W, Flanagan K, Rivero R, Chen T, O'Malley S, Zingaro G, Kivlighn S, Siegl P, Lotti V, Chang R, Greenlee W
Bioorg Med Chem Lett (1994) 4 : 2787 -2792
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.96 8.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL96314 1 8.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL96314 IC50 = 1.1 nM 8.96