Assay Detail
Binding
CHEMBL651296
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Binding affinity for retinoic acid receptor RAR beta
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
An improved synthesis of the C-linked glucuronide of N-(4-hydroxyphenyl)retinamide.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 9.30 | 9.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL38 | TRETINOIN | 4.0 | 1 | 9.30 |
| CHEMBL7301 | FENRETINIDE | 3.0 | 1 | - |
| CHEMBL2303693 | — | — | 1 | - |
| CHEMBL82248 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL38 | TRETINOIN | Ki | = | 0.5 | nM | 9.30 |
| CHEMBL7301 | FENRETINIDE | Ki | > | 2800.0 | nM | - |
| CHEMBL2303693 | — | Ki | > | 2800.0 | nM | - |
| CHEMBL82248 | — | Ki | > | 2800.0 | nM | - |