Assay Detail
Functional
CHEMBL652016
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for its ability to stimulate adenylyl cyclase activity in CHO Beta-3 adrenergic receptor cell membrane.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
BMS-187257, a potent, selective, and novel heterocyclic 3 adrenergic receptor agonist
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.44 | 6.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL72169 | — | — | 1 | 6.20 |
| CHEMBL73220 | — | — | 1 | 5.56 |
| CHEMBL72060 | — | — | 1 | 4.56 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL72169 | — | EC50 | = | 630.0 | nM | 6.20 |
| CHEMBL73220 | — | EC50 | = | 2760.0 | nM | 5.56 |
| CHEMBL72060 | — | EC50 | = | 27595.0 | nM | 4.56 |