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Assay Detail

CHEMBL652033

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Antithrombin III (ATIII)-mediated anti-Xa activity was determined
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Antithrombin-III (CHEMBL1950)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Design and synthesis of a novel synthetic NAPAP-penta-saccharide conjugate displaying a dual antithrombotic action.
Buijsman RC, Basten JE, van Dinther TG, van der Marel GA, van Boeckel CA, van Boom JH.
Bioorg Med Chem Lett (1999) 9 : 2013 -2018
PubMed 10450972 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.24 6.24

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL51173 1 6.24

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL51173 IC50 = 570.0 nM 6.24