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Assay Detail

CHEMBL652037

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
In vitro binding affinity against antithrombin III (AT III) was determined by fluorescence spectroscopy
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Antithrombin-III (CHEMBL1950)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthesis and biological activity of a new anti-factor Xa pentasaccharide with a C-interglycosidic bond
Helmboldt A, Petitou M, Mallet J, Herault J, Lormeau J, Driguez PA, Herbert J, Sinay P
Bioorg Med Chem Lett (1997) 7 : 1507 -1510
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 2 8.64 8.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2303815 1 8.72
CHEMBL2303814 1 8.55

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2303815 Kd = 1.9 nM 8.72
CHEMBL2303814 Kd = 2.8 nM 8.55