Assay Detail
Binding
CHEMBL652337
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Binding affinity towards human Beta-3 adrenergic receptor
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Pharmacological treatment of obesity: therapeutic strategies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 8 | 8.18 | 10.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL303537 | — | — | 1 | 10.22 |
| CHEMBL12998 | L-755507 | — | 1 | 9.37 |
| CHEMBL417613 | — | — | 1 | 8.20 |
| CHEMBL57486 | — | — | 1 | 8.20 |
| CHEMBL61275 | — | — | 1 | 7.52 |
| CHEMBL38538 | — | — | 1 | 7.22 |
| CHEMBL61817 | — | — | 1 | 6.52 |
| CHEMBL59765 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL303537 | — | EC50 | = | 0.06 | nM | 10.22 |
| CHEMBL12998 | L-755507 | EC50 | = | 0.43 | nM | 9.37 |
| CHEMBL417613 | — | EC50 | = | 6.3 | nM | 8.20 |
| CHEMBL57486 | — | EC50 | = | 6.3 | nM | 8.20 |
| CHEMBL61275 | — | EC50 | = | 30.0 | nM | 7.52 |
| CHEMBL38538 | — | EC50 | = | 60.0 | nM | 7.22 |
| CHEMBL61817 | — | EC50 | = | 300.0 | nM | 6.52 |
| CHEMBL59765 | — | EC50 | < | 100.0 | nM | - |