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Assay Detail

CHEMBL652341

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was evaluated for agonistic activity in human Beta-3 adrenergic receptor assay; partial weak agonist
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Beta-3 adrenergic receptor (CHEMBL246)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

3-Pyridylethanolamines: potent and selective human beta 3 adrenergic receptor agonists.
Naylor EM, Colandrea VJ, Candelore MR, Cascieri MA, Colwell LF, Deng L, Feeney WP, Forrest MJ, Hom GJ, MacIntyre DE, Strader CD, Tota L, Wang PR, Wyvratt MJ, Fisher MH, Weber AE.
Bioorg Med Chem Lett (1998) 8 : 3087 -3092
PubMed 9873681 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.35 6.35

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL284782 1 6.35

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL284782 EC50 = 450.0 nM 6.35