Assay Detail

CHEMBL652513

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding

Inhibition of binding to GABA-A Benzodiazepine receptor

ChEMBL ↗

Free Research Context This assay will appear in recent viewed items on this browser. Open the demo workspace to preview project-only review queues.

Research home Demo workspace

Target

GABA-A receptor; anion channel (CHEMBL2093872) ↗

Open DB target context

Use one target anchor to keep assay intent, target linkage, and tested compound review aligned.

Loading context

GABA-A receptor; anion channel (CHEMBL2093872) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target GABA-A receptor; anion channel

CHEMBL2093872

Anchored from Assay target.

Protein identity GABA-A receptor; anion channel

Disease frame Disease evidence pending

Open the live target snapshot or evidence card before reviewing assay metadata so target fit and disease framing stay reusable.

Review focus Open DB context pending

Open the live target snapshot before relying on this target frame across surface handoff.

Open target snapshot Open evidence card Search with this context

Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Confidence	4 — Cell-line / Tissue
Curated By	Autocuration

Target

GABA-A receptor; anion channel (CHEMBL2093872) ↗

Type	PROTEIN COMPLEX GROUP
Organism	Homo sapiens

Publication

Mixture-based synthetic combinatorial libraries.

Houghten RA, Pinilla C, Appel JR, Blondelle SE, Dooley CT, Eichler J, Nefzi A, Ostresh JM.
J Med Chem (1999) 42 : 3743 -3778
PubMed 10508425 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Ki	1	7.77	7.77

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL275638	FLAVONE	2.0	1	7.77

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL275638	FLAVONE	Ki	=	17.0	nM	7.77