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Assay Detail

CHEMBL652793

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Tested for its ability to inhibit antennal esterases of Spodoptera littoralis without pre-incubation
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Spodoptera littoralis
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Inhibition of antennal esterases of the egyptian armyworm Spodoptera littoralis by trifluoromethyl ketones
Duran I, Parrilla A, Feixas J, Guerrero A
Bioorg Med Chem Lett (1993) 3 : 2593 -2598
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 5.12 5.43

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL89506 1 5.43
CHEMBL86998 1 5.10
CHEMBL89613 1 4.97
CHEMBL89508 1 4.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL89506 IC50 = 3700.0 nM 5.43
CHEMBL86998 IC50 = 7900.0 nM 5.10
CHEMBL89613 IC50 = 10600.0 nM 4.97
CHEMBL89508 IC50 = 11000.0 nM 4.96