Assay Detail
Functional
CHEMBL652856
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Effective concentration for retinoic acid receptor RAR beta transcriptional activation
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Synthesis and biological activity of retinoic acid receptor-alpha specific amides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 7.61 | 8.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL69367 | — | — | 1 | 8.05 |
| CHEMBL38 | TRETINOIN | 4.0 | 1 | 7.42 |
| CHEMBL326911 | — | — | 1 | 7.35 |
| CHEMBL107054 | — | — | 1 | - |
| CHEMBL106527 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL69367 | — | EC50 | = | 9.0 | nM | 8.05 |
| CHEMBL38 | TRETINOIN | EC50 | = | 38.0 | nM | 7.42 |
| CHEMBL326911 | — | EC50 | = | 45.0 | nM | 7.35 |
| CHEMBL107054 | — | EC50 | > | 1000.0 | nM | - |
| CHEMBL106527 | — | EC50 | > | 1000.0 | nM | - |